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Abstrak: Trichomonas vaginalis infection was associated with an increased risk of human i
Dipublikasi pada Thursday, 29 March 2007 oleh administrator
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Trichomonas vaginalis infection was associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) infection.
At monthly follow-up visits, laboratory screening for HIV-1 and genital tract infections was conducted. Among 1335 HIV-1–seronegative women monitored for a median of 566 days, there were 806 incident T. vaginalis infections (23.6/100 person-years), and 265 women seroconverted to HIV-1 (7.7/100 person-years).
Trichomoniasis was associated with a 1.52-fold (95% confidence interval, 1.04–2.24-fold) increased risk of HIV-1 acquisition after adjustment for potential confounding factors. Treatment and prevention of T. vaginalis infection could reduce HIV-1 risk in women.
R. Scott McClelland,1,2,3 Laura Sangaré,2 Wisal M. Hassan,3 Ludo Lavreys,2,3 Kishorchandra Mandaliya,5 James Kiarie,4 Jeckoniah Ndinya-Achola,3 Walter Jaoko,3 and Jared M. Baeten1
Departments of 1Medicine and 2Epidemiology, University of Washington, Seattle; Departments of 3Medical Microbiology and 4Obstetrics and Gynaecology, University of Nairobi, Nairobi, and 5Coast Provincial General Hospital, Mombasa, Kenya
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Rata-rata: 3.5
Pemilih: 4
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